PIK3CA-H1047R Antibody
BiCell Scientific
SKU:52731M-50UL
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Scientific Overview
Use this antibody to examine PIK3CA-H1047R when mapping complex behavior and signaling context. PIK3CA-H1047R is a signaling protein that can relay information through phosphorylation and complex assembly. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Tracking PIK3CA-H1047R can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Research Relevance
Signaling targets are typically assessed across time courses to capture transient activation windows. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
When cell-state transitions occur, this target may change alongside partners in the same compartment or pathway neighborhood. In oncology research models, expression shifts can accompany changes in adhesion, signaling, or differentiation state.
When building a narrative around the target, it helps to track:
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
- interaction patterns within multi-protein complexes
Application-Specific Context
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
For challenging targets, pairing PIK3CA-H1047R measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
Choose the regular format format to study PIK3CA-H1047R in a way that stays anchored to pathway logic.
- Targets:
- PIK3CA
- Research Area:
- Cancer • Cell Signaling • Metabolism
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (15-aa) harboring H1047R mutation of human PIK3CA protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P42336
- Homology:
- Synthetic peptide sequence showing 93.3% homology to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C