PIK3R4 (p150) Antibody - FFPE Validated
BiCell Scientific
SKU:52764-FFPE-50UL
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About the Target
Designed to help you assess PIK3R4, this antibody supports studies where protein context matters. PIK3R4 is a signaling protein that can relay information through phosphorylation and complex assembly. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
In some datasets and protocols, it is referenced by the gene symbol p150.
Research Context
Parallel measurement of upstream inputs and downstream readouts can sharpen interpretation of pathway behavior. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- condition-to-condition comparisons with matched controls
- time-resolved changes following stimulation or inhibition
- localization shifts between cytoplasm, membrane, and nucleus
Variant Considerations
For paraffin-embedded samples, fixation history and retrieval strategy matter; this option is aligned to those constraints. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting PIK3R4, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so PIK3R4 patterns can be compared across experiments without guesswork.
The fixed-section version supports deeper biological narratives around PIK3R4 without overcomplicating setup.
- Targets:
- PIK3R4
- Research Area:
- Cell Signaling • Metabolism
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of human PIK3R4 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q99570
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C