Pimethixene maleate

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Selleck Chemicals

S3913-5MG

€144,00 EUR
€144,00 EUR
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Pimethixene maleate is an inhibitor of 5-HT Receptors and Adrenergic Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in cardiovascular and neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.

By inhibiting 5-HT Receptors and Adrenergic Receptors, Pimethixene maleate can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving 5-HT Receptors and Adrenergic Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Pimethixene maleate is appropriate when a defined chemical perturbant is needed to connect 5-HT Receptors and Adrenergic Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
5-HT Receptors • Adrenergic Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Cardiovascular • Neuroscience
CAS No.:
13187-06-9
Molecular Weight:
409.5
Formula:
C₂₃H₂₃NO₄S
SMILES:
CN1CCC(CC1)=C2C3=CC=CC=C3SC4=CC=CC=C24.OC(=O)\C=C/C(O)=O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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