Pioglitazone (U-72107)

1 1

Selleck Chemicals

S2590-10MG

€144,00 EUR
€144,00 EUR
Sale Sold out
Taxes included. Shipping calculated at checkout.
Size
View full details

Pioglitazone (U-72107) is an agonist of PPAR gamma and PPAR used in studies of Hormone Signaling and Metabolic Signaling. In practice, this places the compound in experiments that measure ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in endocrinology and metabolism models.

By activating PPAR gamma and PPAR, Pioglitazone (U-72107) can be used to examine ligand-dependent transcriptional programs and endocrine regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving PPAR gamma and PPAR
  • Pathway perturbation studies connected to Hormone Signaling and Metabolic Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Pioglitazone (U-72107) is appropriate when a defined chemical perturbant is needed to connect PPAR gamma and PPAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
PPAR gamma • PPAR
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling • Metabolic Signaling
Research Area:
Endocrinology • Metabolism
CAS No.:
111025-46-8
Molecular Weight:
356.44
Formula:
C₁₉H₂₀N₂O₃S
SMILES:
CCC1=CN=C(C=C1)CCOC2=CC=C(C=C2)CC3C(=O)NC(=O)S3
InChIKey:
HYAFETHFCAUJAY-UHFFFAOYSA-N
PubChem:
4829
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.