Pirarubicin

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Selleck Chemicals

SKU:S1393-10MG

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Pirarubicin is an inhibitor of DNA/RNA Synthesis and Topoisomerase used in studies of DNA Damage Response. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to checkpoint activation, DNA repair, and genome-stability control in cancer, dna damage / repair, and infectious disease models.

By inhibiting DNA/RNA Synthesis and Topoisomerase, Pirarubicin can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, dna damage / repair, and infectious disease models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DNA/RNA Synthesis and Topoisomerase
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Pirarubicin is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis and Topoisomerase with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, dna damage / repair, and infectious disease models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DNA/RNA Synthesis • Topoisomerase
Target Class:
Enzyme
Pathways:
DNA Damage Response
Research Area:
Cancer • DNA Damage / Repair • Infectious Disease
CAS No.:
72496-41-4
Molecular Weight:
627.64
Formula:
C₃₂H₃₇NO₁₂
SMILES:
CC1C(C(CC(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=CC=C5)OC)O)(C(=O)CO)O)N)OC6CCCCO6
InChIKey:
KMSKQZKKOZQFFG-UHFFFAOYSA-N
PubChem:
11296583
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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