Pirenzepine dihydrochloride
Selleck Chemicals
SKU:S3662-25MG
Couldn't load pickup availability

Pirenzepine dihydrochloride is an inhibitor of AChR used in studies of Neurotransmission. It is especially relevant in cardiovascular and neuroscience models, where defined compound exposure can be linked to synaptic signaling, receptor activity, and neuronal excitability.
By inhibiting AChR, Pirenzepine dihydrochloride can be used to examine synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cardiovascular and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving AChR
- Pathway perturbation studies connected to Neurotransmission
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in cardiovascular and neuroscience models
Overall, Pirenzepine dihydrochloride is appropriate when a defined chemical perturbant is needed to connect AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- AChR
- Target Class:
- Other
- Pathways:
- Neurotransmission
- Research Area:
- Cardiovascular • Neuroscience
- CAS No.:
- 29868-97-1
- Molecular Weight:
- 424.32
- Formula:
- C₁₉H₂₁N₅O₂·2HCl
- SMILES:
- CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.