PLpro inhibitor 

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Selleck Chemicals

S0515-5MG

€419,00 EUR
€419,00 EUR
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PLpro inhibitor&nbsp is an inhibitor of DUB used in studies of Protein Degradation / Proteasome and Viral Entry / Replication. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and host-pathogen interactions, entry mechanisms, and replication-associated responses in cancer, infectious disease, and protein homeostasis models.

By inhibiting DUB, PLpro inhibitor&nbsp can be used to examine ubiquitin-dependent turnover, proteostasis, and targeted protein degradation and host-pathogen interactions, entry mechanisms, and replication-associated responses. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer, infectious disease, and protein homeostasis models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DUB
  • Pathway perturbation studies connected to Protein Degradation / Proteasome and Viral Entry / Replication
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, PLpro inhibitor&nbsp is appropriate when a defined chemical perturbant is needed to connect DUB with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, infectious disease, and protein homeostasis models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DUB
Target Class:
Enzyme
Pathways:
Protein Degradation / Proteasome • Viral Entry / Replication
Research Area:
Cancer • Infectious Disease • Protein Homeostasis
CAS No.:
1093070-14-4
Molecular Weight:
346.42
Formula:
C₂₂H₂₂N₂O₂
SMILES:
CC(NC(=O)C1=C(C)C=CC(=C1)NC(C)=O)C2=CC=CC3=CC=CC=C23
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.