(+)-Dizocilpine (MK 801)Maleate

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Selleck Chemicals

S2876-10MG

€144,00 EUR
€144,00 EUR
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(+)-Dizocilpine (MK 801)Maleate is an antagonist of NMDAR used in studies of Calcium Signaling. In practice, this places the compound in experiments that measure calcium flux, excitability, and secretion-linked signaling in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By blocking NMDAR, (+)-Dizocilpine (MK 801)Maleate can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving NMDAR
  • Pathway perturbation studies connected to Calcium Signaling
  • Receptor-blockade and ligand-competition studies
  • Electrophysiology, ion-flux, and membrane-potential studies

Overall, (+)-Dizocilpine (MK 801)Maleate is appropriate when a defined chemical perturbant is needed to connect NMDAR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
NMDAR
Target Class:
Ion Channel
Pathways:
Calcium Signaling
Research Area:
Neuroscience
CAS No.:
77086-22-7
Molecular Weight:
337.37
Formula:
C₁₆H₁₅N·C₄H₄O₄
SMILES:
CC12C3=CC=CC=C3CC(N1)C4=CC=CC=C24.C(=CC(=O)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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