PNU 282987 HCl

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Selleck Chemicals

SKU:S5930-5MG

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PNU 282987 HCl is an agonist of AChR used in studies of Neurotransmission. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to synaptic signaling, receptor activity, and neuronal excitability in metabolism and neuroscience models.

By activating AChR, PNU 282987 HCl can be used to examine synaptic signaling, receptor activity, and neuronal excitability. This context is compatible with electrophysiology, neurotransmission, and receptor-response assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In metabolism and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving AChR
  • Pathway perturbation studies connected to Neurotransmission
  • Agonist-response and downstream signaling studies
  • Phenotypic profiling in metabolism and neuroscience models

Overall, PNU 282987 HCl is appropriate when a defined chemical perturbant is needed to connect AChR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in metabolism and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
AChR
Target Class:
Other
Pathways:
Neurotransmission
Research Area:
Metabolism • Neuroscience
CAS No.:
123464-89-1
Molecular Weight:
301.21
Formula:
C₁₄H₁₈Cl₂N₂O
SMILES:
C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl.Cl
PubChem:
11243536
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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