Polatuzumab Vedotin-piiq
Selleck Chemicals
SKU:D4012-1MG
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Polatuzumab Vedotin-piiq is an antibody-drug conjugate (ADC) composed of a monoclonal antibody against CD79b (a B cell receptor component) and the anti-mitotic cytotoxic agent monomethyl auristatin (MMAE).
Product overview
It is used for research involving relapsed/refractory diffuse large B-cell lymphoma (DLBCL). The product background identifies the antibody component, target antigen and payload or linker architecture where these details are supplied. This ADC context supports comparison of antigen recognition, payload conjugation and cellular uptake behavior in controlled assay systems, especially when researchers need to distinguish conjugated biologics from unconjugated antibodies or standalone small molecules.
Laboratory context
The listed workflow context supports binding and uptake-oriented laboratory studies where a defined antibody component, cellular target and conjugated payload are relevant to assay planning, including cell-surface binding, cell-uptake and protein-binding experiments, within oncology research.
- Research Area:
- Oncology
- Application:
- Cell Surface Binding • Cell Uptake Studies • Protein Binding
- Formulation:
- 100 mM Pro-Ac, 20mM Arg, pH5.0
- CAS No.:
- 1313206-42-6
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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