PPQ-102
Selleck Chemicals
SKU:S0198-5MG
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PPQ-102 is an inhibitor of CFTR used in studies of ion-channel pharmacology. In practice, this places the compound in experiments that measure ion conductance, membrane potential, and electrophysiological responses in cell signaling models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.
By inhibiting CFTR, PPQ-102 can be used to examine ion conductance, membrane potential, and electrophysiological responses. This target class is commonly examined through electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping. In cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving CFTR
- Concentration-response inhibition and target-dependence studies
- Electrophysiology, ion-flux, and membrane-potential studies
- Phenotypic profiling in cell signaling models
Overall, PPQ-102 is appropriate when a defined chemical perturbant is needed to connect CFTR with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- CFTR
- Target Class:
- Ion Channel
- Research Area:
- Cell Signaling
- CAS No.:
- 931706-15-9
- Molecular Weight:
- 438.48
- Formula:
- C₂₆H₂₂N₄O₃
- SMILES:
- CC1=CC=C(O1)C2C3=C4C(=C(N3C5=CC=CC=C5N2)C6=CC=CC=C6)C(=O)N(C(=O)N4C)C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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