Promazine hydrochloride

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Selleck Chemicals

S5428-25MG

€144,00 EUR
€144,00 EUR
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Promazine hydrochloride is an antagonist of Dopamine Receptors and 5-HT Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.

By blocking Dopamine Receptors and 5-HT Receptors, Promazine hydrochloride can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Dopamine Receptors and 5-HT Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Promazine hydrochloride is appropriate when a defined chemical perturbant is needed to connect Dopamine Receptors and 5-HT Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Dopamine Receptors • 5-HT Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Neuroscience
CAS No.:
53-60-1
Molecular Weight:
320.88
Formula:
C₁₇H₂₀N₂S·HCl
SMILES:
CN(C)CCCN1C2=CC=CC=C2SC3=CC=CC=C31.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.