Propranolol

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Selleck Chemicals

SKU:E5827-100MG

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Propranolol is an antagonist of Adrenergic Receptors used in studies of MAPK / ERK Signaling and GPCR Signaling and related signaling programs. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular, neuroscience, and stem cell biology models.

By blocking Adrenergic Receptors, Propranolol can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and receptor-driven second-messenger signaling and desensitization dynamics. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In cardiovascular, neuroscience, and stem cell biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Adrenergic Receptors
  • Pathway perturbation studies connected to MAPK / ERK Signaling and GPCR Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Propranolol is appropriate when a defined chemical perturbant is needed to connect Adrenergic Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, neuroscience, and stem cell biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Adrenergic Receptors
Target Class:
GPCR
Pathways:
MAPK / ERK Signaling • GPCR Signaling • Neurotransmission
Research Area:
Cardiovascular • Neuroscience • Stem Cell Biology
CAS No.:
525-66-6
Molecular Weight:
259.34
Formula:
C₁₆H₂₁NO₂
SMILES:
CC(C)NCC(O)COc1cccc2ccccc12
InChIKey:
AQHHHDLHHXJYJD-UHFFFAOYSA-N
PubChem:
4946
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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