Protocadherin-15 (PCDH15 or CDHR15 or USH1F or DFNB23) Antibody - FFPE Validated

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BiCell Scientific

50535-FFPE-50UL

€500,00 EUR
€500,00 EUR
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Size
Blocking Peptide
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About the Target

To connect mechanism with measurement, this antibody lets you investigate Protocadherin-15 (USH1F) in pathway-driven studies. Protocadherin-15 is a structural regulator of intercellular boundaries and tissue architecture. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Tracking Protocadherin-15 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.

Research Context

Shifts in junction organization can accompany migration, tissue morphogenesis, and altered mechanical tension. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution. Planar polarity studies may connect this target to directional signaling and cytoskeletal alignment.

Consider these angles when interpreting target-level changes:

  • comparative profiling across cell states or perturbations
  • changes in complex assembly with scaffold or adaptor proteins
  • co-localization patterns with cytoskeletal elements

Variant Considerations

This fixed-section oriented version is intended for paraffin-embedded tissue, where crosslinking and retrieval steps can shape epitope accessibility. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.

To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so Protocadherin-15 patterns can be compared across experiments without guesswork.

When interpreting Protocadherin-15, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

The fixed-section option supports mechanistic reading of Protocadherin-15 (USH1F) when interactions and context are the focus.

Targets:
PCDH15
Research Area:
Cell Signaling • Developmental Biology
Application:
IHC-P
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (13-aa) derived from the C-terminal region of mouse protocadherin-15 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q96QU1
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 69.2% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C