Prucalopride

1 1

Selleck Chemicals

S2875-10MG

€167,00 EUR
€167,00 EUR
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Prucalopride is an agonist of 5-HT Receptors used in studies of GPCR Signaling and Neurotransmission. It is especially relevant in neuroscience models, where defined compound exposure can be linked to receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability.

By activating 5-HT Receptors, Prucalopride can be used to examine receptor-driven second-messenger signaling and desensitization dynamics and synaptic signaling, receptor activity, and neuronal excitability. The gpcr annotation adds relevance to GPCR pharmacology, ligand-binding, and signaling assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving 5-HT Receptors
  • Pathway perturbation studies connected to GPCR Signaling and Neurotransmission
  • Agonist-response and downstream signaling studies
  • GPCR pharmacology, ligand-binding, and signaling assays

Overall, Prucalopride is appropriate when a defined chemical perturbant is needed to connect 5-HT Receptors with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
5-HT Receptors
Target Class:
GPCR
Pathways:
GPCR Signaling • Neurotransmission
Research Area:
Neuroscience
CAS No.:
179474-81-8
Molecular Weight:
367.87
Formula:
C₁₈H₂₆ClN₃O₃
SMILES:
COCCCN1CCC(CC1)NC(=O)C2=CC(=C(C3=C2OCC3)N)Cl
InChIKey:
ZPMNHBXQOOVQJL-UHFFFAOYSA-N
PubChem:
3052762
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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