PT2385

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Selleck Chemicals

S8352-1MG

€144,00 EUR
€144,00 EUR
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PT2385 is an inhibitor of HIF used in studies of pathway modulation. It is especially relevant in cancer, cell signaling, and epigenetics models, where defined compound exposure can be linked to pathway-dependent signal amplification or attenuation.

By inhibiting HIF, PT2385 can be used to examine pathway-dependent signal amplification or attenuation. This target class is commonly examined through pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping. In cancer, cell signaling, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HIF
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies
  • Phenotypic profiling in cancer, cell signaling, and epigenetics models

Overall, PT2385 is appropriate when a defined chemical perturbant is needed to connect HIF with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HIF
Target Class:
Signaling Pathway Modulator
Research Area:
Cancer • Cell Signaling • Epigenetics
CAS No.:
1672665-49-4
Molecular Weight:
383.34
Formula:
C₁₇H₁₂F₃NO₄S
SMILES:
CS(=O)(=O)C1=C2C(C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)(F)F)O
InChIKey:
ONBSHRSJOPSEGS-UHFFFAOYSA-N
PubChem:
91754484
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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