Pyrroloquinoline quinone

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Selleck Chemicals

S3578-5MG

€144,00 EUR
€144,00 EUR
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Pyrroloquinoline quinone is an inhibitor of ROS used in studies of JAK-STAT Signaling and Oxidative Stress Response. It is especially relevant in aging, endocrinology, and immunology models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and redox signaling, ROS handling, and antioxidant defenses.

By inhibiting ROS, Pyrroloquinoline quinone can be used to examine cytokine-responsive transcriptional signaling and immune regulation and redox signaling, ROS handling, and antioxidant defenses. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In aging, endocrinology, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving ROS
  • Pathway perturbation studies connected to JAK-STAT Signaling and Oxidative Stress Response
  • Concentration-response inhibition and target-dependence studies
  • Pathway-reporter and mechanistic-phenotyping studies

Overall, Pyrroloquinoline quinone is appropriate when a defined chemical perturbant is needed to connect ROS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, endocrinology, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
ROS
Target Class:
Signaling Pathway Modulator
Pathways:
JAK-STAT Signaling • Oxidative Stress Response
Research Area:
Aging • Endocrinology • Immunology • Inflammation
CAS No.:
72909-34-3
Molecular Weight:
330.21
Formula:
C₁₄H₆N₂O₈
SMILES:
[O]C1=c2nc(C(=O)O)cc(C(=O)O)c2=C2N=C(C(=O)O)C=C2C1=O
InChIKey:
BFXPAGBRVPZCLS-UHFFFAOYSA-N
PubChem:
1024
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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