QX-314 chloride
Selleck Chemicals
SKU:S7848-5MG
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QX-314 chloride is an activator of TRP Channels and Sodium Channels used in studies of Calcium Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to calcium flux, excitability, and secretion-linked signaling in cardiovascular, cell signaling, and neuroscience models.
By activating TRP Channels and Sodium Channels, QX-314 chloride can be used to examine calcium flux, excitability, and secretion-linked signaling. The ion channel annotation adds relevance to electrophysiology, ion-flux, and membrane-potential studies, together with downstream-response mapping in the same experimental setting. In cardiovascular, cell signaling, and neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving TRP Channels and Sodium Channels
- Pathway perturbation studies connected to Calcium Signaling
- Gain-of-function pathway-activation studies
- Electrophysiology, ion-flux, and membrane-potential studies
Overall, QX-314 chloride is appropriate when a defined chemical perturbant is needed to connect TRP Channels and Sodium Channels with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cardiovascular, cell signaling, and neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- TRP Channels • Sodium Channels
- Target Class:
- Ion Channel
- Pathways:
- Calcium Signaling
- Research Area:
- Cardiovascular • Cell Signaling • Neuroscience
- CAS No.:
- 5369-03-9
- Molecular Weight:
- 298.85
- Formula:
- C₁₆H₂₇ClN₂O
- SMILES:
- [Cl-].CC[N+](CC)(CC)CC(=O)NC1=C(C)C=CC=C1C
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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