R788 (Fostamatinib)Disodium
Selleck Chemicals
SKU:S2206-5MG
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R788 (Fostamatinib)Disodium is an inhibitor of SYK used in studies of MAPK / ERK Signaling and Immune Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses in angiogenesis, cancer, and cell signaling models.
By inhibiting SYK, R788 (Fostamatinib)Disodium can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling and cytokine-mediated signaling and inflammatory effector responses. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In angiogenesis, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving SYK
- Pathway perturbation studies connected to MAPK / ERK Signaling and Immune Signaling
- Concentration-response inhibition and target-dependence studies
- Biochemical kinase assays, phospho-signaling studies, and selectivity profiling
Overall, R788 (Fostamatinib)Disodium is appropriate when a defined chemical perturbant is needed to connect SYK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- SYK
- Target Class:
- Kinase
- Pathways:
- MAPK / ERK Signaling • Immune Signaling
- Research Area:
- Angiogenesis • Cancer • Cell Signaling • Immunology
- CAS No.:
- 1025687-58-4
- Molecular Weight:
- 624.42
- Formula:
- C₂₃H₂₄FN₆O₉P·2Na
- SMILES:
- CC1(C(=O)N(C2=C(O1)C=CC(=N2)NC3=NC(=NC=C3F)NC4=CC(=C(C(=C4)OC)OC)OC)COP(=O)([O-])[O-])C.[Na+].[Na+]
- PubChem:
- 11671467
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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