Resatorvid (TAK-242)

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Selleck Chemicals

S7455-5MG

€154,00 EUR
€154,00 EUR
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Resatorvid (TAK-242) is an inhibitor of TNF-alpha and Interleukins and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. In practice, this places the compound in experiments that measure cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling in autophagy, immunology, and inflammation models.

By inhibiting TNF-alpha and Interleukins and related targets, Resatorvid (TAK-242) can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In autophagy, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TNF-alpha and Interleukins and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, Resatorvid (TAK-242) is appropriate when a defined chemical perturbant is needed to connect TNF-alpha and Interleukins and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in autophagy, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TNF-alpha • Interleukins • TLR
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Autophagy • Immunology • Inflammation
CAS No.:
243984-11-4
Molecular Weight:
361.82
Formula:
C₁₅H₁₇ClFNO₄S
SMILES:
CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl
InChIKey:
LEEIJTHMHDMWLJ-UHFFFAOYSA-N
PubChem:
11703255
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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