RET51 (RET or CDHF12 or CDHR16) Antibody - FFPE Validated

Protein Function

Plan your comparisons around RET51 and use this antibody to characterize state-dependent differences. RET51 is a regulator within kinase-driven cascades that influence transcriptional and metabolic responses. Plan positive and negative controls that match your model system, including perturbations expected to shift the target.

In some datasets and protocols, it is referenced by the gene symbol CDHF12.

Experimental Applications

Signaling targets are typically assessed across time courses to capture transient activation windows. Time course design can be decisive when regulation is transient or compartment dependent.

Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.

Common experimental questions that benefit from target tracking include:

• localization shifts between cytoplasm, membrane, and nucleus
• time-resolved changes following stimulation or inhibition
• condition-to-condition comparisons with matched controls

Workflow Perspective

In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. Predefine acceptance criteria for controls before collecting the full dataset.

If your study spans multiple model systems, it can help to define a shared reference condition for RET51 so cross-sample contrasts stay meaningful.

The fixed-section format fits designs where RET51 is evaluated with deliberate controls and careful comparisons.