RG3039

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Selleck Chemicals

S0063-5MG

€144,00 EUR
€144,00 EUR
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RG3039 is an inhibitor of DNA/RNA Synthesis used in studies of DNA Damage Response. It is especially relevant in cancer and dna damage / repair models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control.

By inhibiting DNA/RNA Synthesis, RG3039 can be used to examine checkpoint activation, DNA repair, and genome-stability control. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cancer and dna damage / repair models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving DNA/RNA Synthesis
  • Pathway perturbation studies connected to DNA Damage Response
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, RG3039 is appropriate when a defined chemical perturbant is needed to connect DNA/RNA Synthesis with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and dna damage / repair models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
DNA/RNA Synthesis
Target Class:
Enzyme
Pathways:
DNA Damage Response
Research Area:
Cancer • DNA Damage / Repair
CAS No.:
1005504-62-0
Molecular Weight:
432.35
Formula:
C₂₁H₂₃Cl₂N₅O
SMILES:
C1CN(CCC1COC2=CC=CC3=C2C(=NC(=N3)N)N)CC4=C(C=CC=C4Cl)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.

The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.