RGD peptide (GRGDNP)
Selleck Chemicals
SKU:S4513-5MG
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RGD peptide (GRGDNP) is a peptide-based inhibitor of Integrins used in studies of Apoptosis. It is especially relevant in angiogenesis, apoptosis, and cancer models, where defined compound exposure can be linked to caspase-associated cell-death signaling and survival decisions.
By inhibiting Integrins, RGD peptide (GRGDNP) can be used to examine caspase-associated cell-death signaling and survival decisions. This context is compatible with apoptosis, viability, and caspase-readout assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In angiogenesis, apoptosis, and cancer models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving Integrins
- Pathway perturbation studies connected to Apoptosis
- Concentration-response inhibition and target-dependence studies
- Phenotypic profiling in angiogenesis, apoptosis, and cancer models
Overall, RGD peptide (GRGDNP) is appropriate when a defined chemical perturbant is needed to connect Integrins with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in angiogenesis, apoptosis, and cancer models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- Integrins
- Target Class:
- Other
- Pathways:
- Apoptosis
- Research Area:
- Angiogenesis • Apoptosis • Cancer
- CAS No.:
- 114681-65-1
- Molecular Weight:
- 614.61
- Formula:
- C₂₃H₃₈N₁₀O₁₀
- SMILES:
- NCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)N1CCCC1C(O)=O
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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