RN-1734

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Selleck Chemicals

S2650-5MG

€144,00 EUR
€144,00 EUR
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RN-1734 is an antagonist of TRP Channels and TNF-alpha and related targets used in studies of JAK-STAT Signaling and NF-kB Signaling and related signaling programs. It is especially relevant in cell signaling, immunology, and inflammation models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling.

By blocking TRP Channels and TNF-alpha and related targets, RN-1734 can be used to examine cytokine-responsive transcriptional signaling and immune regulation and inflammatory transcriptional control and stress-responsive survival signaling. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cell signaling, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving TRP Channels and TNF-alpha and related targets
  • Pathway perturbation studies connected to JAK-STAT Signaling and NF-kB Signaling and related signaling programs
  • Receptor-blockade and ligand-competition studies
  • Immune-cell activation, cytokine, and mediator assays

Overall, RN-1734 is appropriate when a defined chemical perturbant is needed to connect TRP Channels and TNF-alpha and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
TRP Channels • TNF-alpha • Interleukins
Target Class:
Immunomodulator
Pathways:
JAK-STAT Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Cell Signaling • Immunology • Inflammation • Neuroscience
CAS No.:
946387-07-1
Molecular Weight:
353.31
Formula:
C₁₄H₂₂Cl₂N₂O₂S
SMILES:
CC(C)NCCN(C(C)C)S(=O)(=O)C1=C(C=C(C=C1)Cl)Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.