Romidepsin (FK228)

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Selleck Chemicals

S3020-1MG

€193,00 EUR
€193,00 EUR
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Romidepsin (FK228) is an inhibitor of HDAC used in studies of Apoptosis and Epigenetic Regulation. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation in apoptosis, cancer, and epigenetics models.

By inhibiting HDAC, Romidepsin (FK228) can be used to examine caspase-associated cell-death signaling and survival decisions and chromatin-state control, histone modification, and transcriptional regulation. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In apoptosis, cancer, and epigenetics models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving HDAC
  • Pathway perturbation studies connected to Apoptosis and Epigenetic Regulation
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, Romidepsin (FK228) is appropriate when a defined chemical perturbant is needed to connect HDAC with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in apoptosis, cancer, and epigenetics models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
HDAC
Target Class:
Epigenetic Regulator
Pathways:
Apoptosis • Epigenetic Regulation
Research Area:
Apoptosis • Cancer • Epigenetics
CAS No.:
128517-07-7
Molecular Weight:
540.7
Formula:
C₂₄H₃₆N₄O₆S₂
SMILES:
CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C
InChIKey:
OHRURASPPZQGQM-UHFFFAOYSA-N
PubChem:
57515973
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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