RYR1 (RYR) Antibody
BiCell Scientific
SKU:54011-50UL
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Biological Background
This antibody is suited for researchers who want to explore RYR1 and relate it to cell-state biology. RYR1 is a molecular target often examined to connect phenotype changes with underlying protein regulation. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Tracking RYR1 can clarify whether changes reflect regulation, redistribution, or altered complex assembly.
Use in the Laboratory
In many projects, target-level measurements help link perturbations to downstream phenotypes. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Depending on the model, researchers may ask whether signal shifts reflect altered abundance, compartment changes, or remodeling of associated complexes.
To keep datasets interpretable, labs often document:
- baseline versus stimulated condition comparisons
- subcellular compartment mapping
- cross-sample normalization strategies
Version Notes
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. Small differences in preparation can reshape apparent localization, so interpret results in context.
For challenging targets, pairing RYR1 measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
If your study spans multiple model systems, it can help to define a shared reference condition for RYR1 so cross-sample contrasts stay meaningful.
The regular format version supports deeper biological narratives around RYR1 without overcomplicating setup.
- Targets:
- RYR1
- Research Area:
- Cell Signaling
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the N-terminal cytoplasmic region of human RYR1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P21817
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C