S961

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Selleck Chemicals

SKU:S6922-1MG

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S961 is an antagonist of Insulin Receptor used in studies of PI3K-Akt-mTOR Signaling. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs in cancer, cell signaling, and endocrinology models.

By blocking Insulin Receptor, S961 can be used to examine growth-factor signaling, survival control, and nutrient-sensing outputs. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Insulin Receptor
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling
  • Receptor-blockade and ligand-competition studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, S961 is appropriate when a defined chemical perturbant is needed to connect Insulin Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Insulin Receptor
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling
Research Area:
Cancer • Cell Signaling • Endocrinology • Metabolism
CAS No.:
1083433-49-1
Molecular Weight:
4804.13
Formula:
C₂₁₁H₂₉₇N₅₅O₇₁S₂
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.