SAR407899 hydrochloride

1 1

Selleck Chemicals

E2385-5MG

€144,00 EUR
€144,00 EUR
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SAR407899 hydrochloride is an inhibitor of Rho GTPases and ROCK used in studies of target-focused biology. In practice, this places the compound in experiments that measure annotated target biology and downstream cellular responses in cancer, cardiovascular, and cell cycle models.

By inhibiting Rho GTPases and ROCK, SAR407899 hydrochloride can be used to examine annotated target biology and downstream cellular responses. That positioning is consistent with concentration-response inhibition and target-dependence studies and with follow-up studies that compare concentration-dependent responses across orthogonal assay formats. In cancer, cardiovascular, and cell cycle models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Rho GTPases and ROCK
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cardiovascular, and cell cycle models
  • Combination studies with orthogonal perturbagens

Overall, SAR407899 hydrochloride is appropriate when a defined chemical perturbant is needed to connect Rho GTPases and ROCK with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cardiovascular, and cell cycle models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Rho GTPases • ROCK
Target Class:
Other
Research Area:
Cancer • Cardiovascular • Cell Cycle • Cell Signaling
CAS No.:
923262-96-8
Molecular Weight:
280.75
Formula:
C₁₄H₁₆N₂O₂·ClH
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.