SBI-0640756

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Selleck Chemicals

S8181-2MG

€105,00 EUR
€105,00 EUR
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SBI-0640756 is an inhibitor linked to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs and related pathway-oriented research. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling in cancer, cell cycle, and immunology models.

The pathway annotation connects SBI-0640756 to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs, supporting experiments that monitor growth-factor signaling, survival control, and nutrient-sensing outputs and inflammatory transcriptional control and stress-responsive survival signaling across biochemical, cellular, or phenotypic assay formats. This context is compatible with AKT/mTOR readouts, pathway-response, and viability assays and NF-kB reporter, cytokine, and inflammation assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer, cell cycle, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Phenotypic profiling in cancer, cell cycle, and immunology models
  • Combination studies with orthogonal perturbagens

Overall, SBI-0640756 is well suited to pathway-oriented studies that need a defined compound input for PI3K-Akt-mTOR Signaling and NF-kB Signaling and related signaling programs readouts in cancer, cell cycle, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
PI3K-Akt-mTOR Signaling • NF-kB Signaling • Immune Signaling
Research Area:
Cancer • Cell Cycle • Immunology • Inflammation
CAS No.:
1821280-29-8
Molecular Weight:
404.82
Formula:
C₂₃H₁₄ClFN₂O₂
SMILES:
C1=CC=C(C=C1)C2=C(C(=O)NC3=C2C=C(C=C3)Cl)C(=O)C=CC4=CC(=CN=C4)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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