SC99
Selleck Chemicals
SKU:S1349-25MG
Couldn't load pickup availability

SC99 is an inhibitor of STAT and JAK2 used in studies of JAK-STAT Signaling. It is especially relevant in cancer, cell signaling, and immunology models, where defined compound exposure can be linked to cytokine-responsive transcriptional signaling and immune regulation.
By inhibiting STAT and JAK2, SC99 can be used to examine cytokine-responsive transcriptional signaling and immune regulation. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and immunology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving STAT and JAK2
- Pathway perturbation studies connected to JAK-STAT Signaling
- Concentration-response inhibition and target-dependence studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, SC99 is appropriate when a defined chemical perturbant is needed to connect STAT and JAK2 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and immunology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- STAT • JAK2
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- JAK-STAT Signaling
- Research Area:
- Cancer • Cell Signaling • Immunology • Inflammation
- CAS No.:
- 882290-02-0
- Molecular Weight:
- 336.15
- Formula:
- C₁₅H₈Cl₂FN₃O
- SMILES:
- FC1=C(Cl)C=C(N/N=C(C#N)/C(=O)C2=CC=C(Cl)C=C2)C=C1
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
Products may be subject to intellectual property rights.
The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.