SCN2A (Nav1.2) Antibody
BiCell Scientific
SKU:20352-50UL
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Protein Function
To connect mechanism with measurement, this antibody lets you assess SCN2A in pathway-driven studies. SCN2A is a channel or transporter associated with regulated flux across cellular membranes. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Monitoring SCN2A alongside context markers can improve interpretation when phenotypes are subtle.
Experimental Applications
Modulators that affect trafficking, phosphorylation, or ligand binding can change apparent distribution and signal intensity. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Many workflows benefit from tracking both signal intensity and compartment distribution, especially when the target participates in multi-protein assemblies.
Common experimental questions that benefit from target tracking include:
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
- stimulus-dependent trafficking and turnover
Workflow Perspective
If your project spans exploratory questions, the regular version offers a balanced option for establishing baseline signal behavior. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
For challenging targets, pairing SCN2A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
When interpreting SCN2A, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Choose the regular format format to study SCN2A in a way that stays anchored to pathway logic.
- Targets:
- SCN2A
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (14-aa) derived from the C-terminal region of human Nav1.2 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q99250
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C