SCN5A (Nav1.5) Antibody
BiCell Scientific
SKU:20355-50UL
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About the Target
Designed to help you analyze SCN5A, this antibody supports studies where protein context matters. SCN5A is a membrane-embedded regulator of ionic or osmotic balance in cells. Its behavior can reflect changes in differentiation state, stress, or remodeling of cellular architecture.
Following SCN5A across perturbations can help separate expression effects from compartment shifts.
Research Context
Comparisons across tissues or engineered cell lines can help separate expression effects from localization effects. Because regulation can be multi-layered, combining abundance and localization information can sharpen conclusions.
Consider these angles when interpreting target-level changes:
- relative abundance across engineered constructs
- surface versus intracellular pool distribution
- patterns consistent with apical or basolateral sorting
Variant Considerations
This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
For challenging targets, pairing SCN5A measurements with a second marker can clarify whether differences arise from regulation, redistribution, or shifts in cell composition within the sample.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SCN5A patterns can be compared across experiments without guesswork.
As you refine hypotheses around SCN5A, the regular format format helps keep conclusions tied to preparation context.
- Targets:
- SCN5A
- Research Area:
- Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the C-terminal region of human Nav1.5 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q14524
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C