Serclutamab Talirine
Selleck Chemicals
SKU:D4027-1MG
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Serclutamab Talirine is an antibody-drug conjugate (ADC) composed of a humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker.
Product overview
Serclutamab Talirine is relevant to research on advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands. The product background identifies the antibody component, target antigen and payload or linker architecture where these details are supplied. This ADC context supports comparison of antigen recognition, payload conjugation and cellular uptake behavior in controlled assay systems, especially when researchers need to distinguish conjugated biologics from unconjugated antibodies or standalone small molecules.
Laboratory context
The listed workflow context supports binding and uptake-oriented laboratory studies where a defined antibody component, cellular target and conjugated payload are relevant to assay planning, including protein-binding, cell-uptake and SPR experiments.
- Application:
- Protein Binding • Cell Uptake Studies • SPR
- Formulation:
- 1xPBS
- CAS No.:
- 2140174-56-5
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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