Sertraline HCl

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Selleck Chemicals

SKU:S4053-10MG

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Sertraline HCl is an inhibitor of Serotonin Transporter used in studies of Neurotransmission. In practice, this places the compound in experiments that measure synaptic signaling, receptor activity, and neuronal excitability in neuroscience models. Dose-response comparison, orthogonal validation, and secondary assay follow-up can further sharpen mechanistic interpretation.

By inhibiting Serotonin Transporter, Sertraline HCl can be used to examine synaptic signaling, receptor activity, and neuronal excitability. The transporter annotation adds relevance to transport, uptake/efflux, and permeability assays, together with downstream-response mapping in the same experimental setting. In neuroscience models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Serotonin Transporter
  • Pathway perturbation studies connected to Neurotransmission
  • Concentration-response inhibition and target-dependence studies
  • Transport, uptake/efflux, and permeability assays

Overall, Sertraline HCl is appropriate when a defined chemical perturbant is needed to connect Serotonin Transporter with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in neuroscience models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Serotonin Transporter
Target Class:
Transporter
Pathways:
Neurotransmission
Research Area:
Neuroscience
CAS No.:
79559-97-0
Molecular Weight:
342.69
Formula:
C₁₇H₁₇Cl₂N·HCl
SMILES:
CNC1CCC(C2=CC=CC=C12)C3=CC(=C(C=C3)Cl)Cl.Cl
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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