Setidegrasib (ASP3082)

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    Selleck Chemicals

    E4757-1MG

    €194,00 EUR
    €194,00 EUR
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    Setidegrasib (ASP3082) is a modulator of KRAS used in studies of MAPK / ERK Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.

    By modulating KRAS, Setidegrasib (ASP3082) can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. This context is compatible with phosphorylation mapping, pathway-response, and growth assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

    Research Applications

    • Target-focused assays involving KRAS
    • Pathway perturbation studies connected to MAPK / ERK Signaling
    • Context-dependent response profiling and mechanism comparison
    • Phenotypic profiling in cancer and cell signaling models

    Overall, Setidegrasib (ASP3082) is appropriate when a defined chemical perturbant is needed to connect KRAS with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

    Targets:
    KRAS
    Target Class:
    Other
    Pathways:
    MAPK / ERK Signaling
    Research Area:
    Cancer • Cell Signaling
    CAS No.:
    2821793-99-9
    Molecular Weight:
    1117.30
    Formula:
    C₆₀H₆₅FN₁₂O₇S
    Storage Temperature:
    -20°C

    For Research Use Only. Not intended for diagnostic or therapeutic use.
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    The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.