SGC 0946

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Selleck Chemicals

SKU:S7079-10MG

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SGC 0946 is an inhibitor of Histone Methyltransferases and Transferases used in studies of Epigenetic Regulation and Metabolic Signaling. In practice, this places the compound in experiments that measure chromatin-state control, histone modification, and transcriptional regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis in cancer, epigenetics, and metabolism models.

By inhibiting Histone Methyltransferases and Transferases, SGC 0946 can be used to examine chromatin-state control, histone modification, and transcriptional regulation and metabolic regulation, energy sensing, and enzyme-linked homeostasis. The epigenetic regulator annotation adds relevance to chromatin, epigenetic, and gene-expression profiling, together with downstream-response mapping in the same experimental setting. In cancer, epigenetics, and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Histone Methyltransferases and Transferases
  • Pathway perturbation studies connected to Epigenetic Regulation and Metabolic Signaling
  • Concentration-response inhibition and target-dependence studies
  • Chromatin, epigenetic, and gene-expression profiling

Overall, SGC 0946 is appropriate when a defined chemical perturbant is needed to connect Histone Methyltransferases and Transferases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, epigenetics, and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Histone Methyltransferases • Transferases
Target Class:
Epigenetic Regulator
Pathways:
Epigenetic Regulation • Metabolic Signaling
Research Area:
Cancer • Epigenetics • Metabolism
CAS No.:
1561178-17-3
Molecular Weight:
618.57
Formula:
C₂₈H₄₀BrN₇O₄
SMILES:
CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=C(C4=C(N=CN=C43)N)Br)O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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