SGLT1 (Slc5a1) (Human) Antibody - FFPE Validated
BiCell Scientific
SKU:20801H-FFPE-50UL
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About the Target
This antibody enables you to examine SGLT1 (Slc5a1) with a direct, biology-first readout. SGLT1 is a trafficking-sensitive transporter that can shift between intracellular pools and the plasma membrane. Look for shifts in distribution that track with phenotype changes.
In some datasets and protocols, it is referenced by the gene symbol Slc5a1.
Research Context
Many transport proteins cycle through endosomal pathways, making localization a key readout alongside abundance. Pair measurements with orthogonal readouts when interpretation is sensitive to context.
Consider these angles when interpreting target-level changes:
- relative abundance across engineered constructs
- stimulus-dependent trafficking and turnover
- patterns consistent with apical or basolateral sorting
- surface versus intracellular pool distribution
Variant Considerations
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. This matters because epitope exposure and background can vary with preparation and extraction steps. If you compare conditions, keep processing steps uniform to support clean interpretation.
When interpreting SGLT1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
If your study spans multiple model systems, it can help to define a shared reference condition for SGLT1 so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SGLT1 patterns can be compared across experiments without guesswork.
With a clear focus on SGLT1 (Slc5a1), this fixed-section option fits streamlined studies and fast iteration.
- Targets:
- SLC5A1
- Research Area:
- Cell Signaling • Metabolism
- Application:
- IHC-P
- Reactivity:
- Human
- Host:
- Rabbit
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal extracellular region of human Sglt1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P13866
- Homology:
- Synthetic peptide sequence showing 62.5% homology to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C