SHANK1 (Synamon) Antibody
BiCell Scientific
SKU:15121-50UL
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About the Target
Build reproducible readouts by using this antibody to assess SHANK1 (Synamon) across matched sample sets. SHANK1 is a neuron-enriched target connected to synaptic organization and signaling dynamics. Use matched handling so differences reflect biology rather than processing.
Following SHANK1 across perturbations can help separate expression effects from compartment shifts.
Research Context
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Consider these angles when interpreting target-level changes:
- comparison across differentiation time courses
- interaction tendencies with scaffold or receptor partners
- regional localization along neurites and synaptic compartments
- activity-linked changes in abundance or distribution
Variant Considerations
For broad method development, the regular format can help you benchmark target behavior before narrowing to a specific readout style. This matters because epitope exposure and background can vary with preparation and extraction steps. Standardize key parameters so differences reflect biology rather than handling.
If your study spans multiple model systems, it can help to define a shared reference condition for SHANK1 so cross-sample contrasts stay meaningful.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SHANK1 patterns can be compared across experiments without guesswork.
With consistent handling, the regular format format can make SHANK1 (Synamon) comparisons easier to reproduce across runs.
- Targets:
- SHANK1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- IF • IHC • WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of human SHANK1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y566
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C