SHANK1 (Synamon) Antibody - Western Blot Validated
BiCell Scientific
SKU:15121-WB-50UL
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Protein Function
To connect mechanism with measurement, this antibody lets you assess SHANK1 in pathway-driven studies. SHANK1 is a signaling component often monitored in models of neuronal differentiation and plasticity. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
In some datasets and protocols, it is referenced by the gene symbol Synamon.
Experimental Applications
Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Target-centric readouts can be framed around localization, relative abundance, or complex behavior, depending on the question you are testing. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Common experimental questions that benefit from target tracking include:
- comparison across differentiation time courses
- regional localization along neurites and synaptic compartments
- interaction tendencies with scaffold or receptor partners
Workflow Perspective
For size-resolved readouts under denaturing conditions, this version helps you focus on expected band patterns and molecular weight regions. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.
When interpreting SHANK1, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.
Use the denaturing-format version to relate SHANK1 behavior to upstream cues and downstream consequences.
- Targets:
- SHANK1
- Research Area:
- Cell Signaling • Neuroscience
- Application:
- WB
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of human SHANK1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- Q9Y566
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C