SHANK2 Antibody

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BiCell Scientific

SKU:15122-50UL

Regular price €305,00 EUR
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Size
Blocking Peptide
Quantity
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Protein Function

To connect mechanism with measurement, this antibody lets you characterize SHANK2 in pathway-driven studies. SHANK2 is a signaling component often monitored in models of neuronal differentiation and plasticity. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.

Monitoring SHANK2 alongside context markers can improve interpretation when phenotypes are subtle.

Experimental Applications

Because many neuronal proteins form complexes, interpreting signal changes can benefit from complementary controls and timing. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.

In practice, target tracking can support localization mapping, relative quantification, and interaction-focused experiments without locking you into a single readout strategy. Neural differentiation and synaptic organization projects may include this target as a contextual readout.

Common experimental questions that benefit from target tracking include:

  • comparison across differentiation time courses
  • activity-linked changes in abundance or distribution
  • interaction tendencies with scaffold or receptor partners

Workflow Perspective

This regular format is a practical starting point when you want flexibility across sample types and iterative optimization. To keep comparisons consistent, align sample preparation steps and define a clear baseline for each series. If interactions are a focus, consider parallel readouts for key partners.

When interpreting SHANK2, consider whether changes track with compartment identity, cell density, or perturbation timing; these factors can influence apparent signal without implying a direct causal link.

The regular format option supports mechanistic reading of SHANK2 when interactions and context are the focus.

Targets:
SHANK2
Research Area:
Cell Signaling • Neuroscience
Application:
IF • IHC • WB
Reactivity:
Mouse • Rat
Host:
Rat
Clonality:
Polyclonal
Isotype:
IgG
Immunogen:
Synthetic peptide (14-aa) derived from the N-terminal region of mouse SHANK2 protein
Conjugation:
Unconjugated
Purification:
Affinity Chromatography
Concentration:
0.25 mg/ml
UniProt:
Q9UPX8
Homology:
Synthetic peptide sequence is identical to rat sequence (showing 42.8% homology to human sequence)
Storage Buffer:
PBS, pH 7.2, 0.1% Sodium Azide
Storage Temperature:
-20°C