SL-327

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Selleck Chemicals

S1066-5MG

€144,00 EUR
€144,00 EUR
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SL-327 is an inhibitor of MEK and MEK1 and related targets used in studies of MAPK / ERK Signaling. It is especially relevant when investigators need a named chemical input and interpretable readouts connected to mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer and cell signaling models.

By inhibiting MEK and MEK1 and related targets, SL-327 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving MEK and MEK1 and related targets
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, SL-327 is appropriate when a defined chemical perturbant is needed to connect MEK and MEK1 and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
MEK • MEK1 • MEK2
Target Class:
Kinase
Pathways:
MAPK / ERK Signaling
Research Area:
Cancer • Cell Signaling
CAS No.:
305350-87-2
Molecular Weight:
335.35
Formula:
C₁₆H₁₂F₃N₃S
SMILES:
C1=CC=C(C(=C1)C(=C(N)SC2=CC=C(C=C2)N)C#N)C(F)(F)F
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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