SLIT1 Antibody - FFPE Validated
BiCell Scientific
SKU:50841-FFPE-50UL
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Biological Background
This antibody helps you characterize SLIT1 while keeping condition-to-condition contrasts straightforward. SLIT1 is a receptor or synapse-associated protein that supports neuronal signaling and connectivity. Use matched handling so differences reflect biology rather than processing.
Following SLIT1 across perturbations can help separate expression effects from compartment shifts.
Use in the Laboratory
Perturbations that alter activity or trafficking can shift localization between soma, neurites, and synaptic regions. Define inclusion criteria and controls early so replicate sets remain interpretable as the dataset grows. Neural differentiation and synaptic organization projects may include this target as a contextual readout.
Interpreting changes can benefit from separating expression differences from redistribution, particularly when the target cycles between compartments.
To keep datasets interpretable, labs often document:
- regional localization along neurites and synaptic compartments
- interaction tendencies with scaffold or receptor partners
- activity-linked changes in abundance or distribution
- comparison across differentiation time courses
Version Notes
In sectioned tissue workflows, interpretation often depends on morphology; this format supports that style of readout. If your study compares multiple conditions, keep acquisition and processing settings stable to avoid confounding. A brief pilot run can help set exposure ranges and reduce reruns later.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SLIT1 patterns can be compared across experiments without guesswork.
For multi-run studies, the fixed-section option helps keep SLIT1 trends comparable from experiment to experiment.
- Targets:
- SLIT1
- Research Area:
- Cell Signaling • Developmental Biology • Neuroscience
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (17-aa) derived from the C-terminal region of mouse SLIT1 protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- O75093
- Homology:
- Synthetic peptide sequence is identical to rat sequence (showing 94.1% homology to human sequence)
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C