Sobetirome

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Selleck Chemicals

E7120-5MG

€193,00 EUR
€193,00 EUR
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Sobetirome is an agonist of Thyroid Hormone Receptor used in studies of Hormone Signaling. It is especially relevant in endocrinology models, where defined compound exposure can be linked to ligand-dependent transcriptional programs and endocrine regulation.

By activating Thyroid Hormone Receptor, Sobetirome can be used to examine ligand-dependent transcriptional programs and endocrine regulation. The nuclear receptor annotation adds relevance to reporter-gene, receptor-binding, and transcriptional assays, together with downstream-response mapping in the same experimental setting. In endocrinology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Thyroid Hormone Receptor
  • Pathway perturbation studies connected to Hormone Signaling
  • Agonist-response and downstream signaling studies
  • Reporter-gene, receptor-binding, and transcriptional assays

Overall, Sobetirome is appropriate when a defined chemical perturbant is needed to connect Thyroid Hormone Receptor with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in endocrinology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Thyroid Hormone Receptor
Target Class:
Nuclear Receptor
Pathways:
Hormone Signaling
Research Area:
Endocrinology
CAS No.:
211110-63-3
Molecular Weight:
328.40
Formula:
C₂₀H₂₄O₄
SMILES:
Cc1cc(OCC(=O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1
InChIKey:
QNAZTOHXCZPOSA-UHFFFAOYSA-N
PubChem:
9862248
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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