Sodium L-Ascorbyl-2-Phosphate (SAP)

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Selleck Chemicals

SKU:S5115-25MG

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Sodium L-Ascorbyl-2-Phosphate (SAP) is a research compound associated with c-Met and is relevant to studies of PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs. In practice, this places the compound in experiments that measure growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cancer, cell signaling, and oxidative stress models.

The current annotation links Sodium L-Ascorbyl-2-Phosphate (SAP) to c-Met, supporting target-focused studies that measure growth-factor signaling, survival control, and nutrient-sensing outputs and mitogenic kinase cascades, proliferation control, and differentiation-linked signaling without assigning a more specific primary mechanism than the dataset provides. The kinase annotation adds relevance to biochemical kinase assays, phospho-signaling studies, and selectivity profiling, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and oxidative stress models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving c-Met
  • Pathway perturbation studies connected to PI3K-Akt-mTOR Signaling and MAPK / ERK Signaling and related signaling programs
  • Metabolite supplementation and biochemical reference studies
  • Biochemical kinase assays, phospho-signaling studies, and selectivity profiling

Overall, Sodium L-Ascorbyl-2-Phosphate (SAP) is appropriate when a defined chemical perturbant is needed to connect c-Met with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and oxidative stress models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
c-Met
Target Class:
Kinase
Pathways:
PI3K-Akt-mTOR Signaling • MAPK / ERK Signaling • Oxidative Stress Response
Research Area:
Cancer • Cell Signaling • Oxidative Stress
CAS No.:
66170-10-3
Molecular Weight:
322.05
Formula:
C₆H₆O₉P·3Na
SMILES:
C(C(C1C(=C(C(=O)O1)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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