Sparsentan (PS-433540, RE-021)

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Selleck Chemicals

S6665-2MG

€265,00 EUR
€265,00 EUR
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Sparsentan (PS-433540, RE-021) is an antagonist linked to GPCR Signaling and related pathway-oriented research. In practice, this places the compound in experiments that measure receptor-driven second-messenger signaling and desensitization dynamics in cardiovascular models.

The pathway annotation connects Sparsentan (PS-433540, RE-021) to GPCR Signaling, supporting experiments that monitor receptor-driven second-messenger signaling and desensitization dynamics across biochemical, cellular, or phenotypic assay formats. This context is compatible with ligand-response, cAMP, calcium-flux, and receptor-pharmacology assays, as well as transcriptional, biochemical, or phenotypic comparisons linked to the annotated pathway state. In cardiovascular models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Pathway perturbation studies connected to GPCR Signaling
  • Receptor-blockade and ligand-competition studies
  • Phenotypic profiling in cardiovascular models
  • Combination studies with orthogonal perturbagens

Overall, Sparsentan (PS-433540, RE-021) is well suited to pathway-oriented studies that need a defined compound input for GPCR Signaling readouts in cardiovascular models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Pathways:
GPCR Signaling
Research Area:
Cardiovascular
CAS No.:
254740-64-2
Molecular Weight:
592.75
Formula:
C₃₂H₄₀N₄O₅S
SMILES:
CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC(=C(C=C3)C4=CC=CC=C4S(=O)(=O)NC5=NOC(=C5C)C)COCC
InChIKey:
WRFHGDPIDHPWIQ-UHFFFAOYSA-N
PubChem:
10257882
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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