SPI-112

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Selleck Chemicals

SKU:S0244-5MG

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SPI-112 is an inhibitor of Phosphatases used in studies of MAPK / ERK Signaling. In practice, this places the compound in experiments that measure mitogenic kinase cascades, proliferation control, and differentiation-linked signaling in cell signaling and metabolism models.

By inhibiting Phosphatases, SPI-112 can be used to examine mitogenic kinase cascades, proliferation control, and differentiation-linked signaling. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In cell signaling and metabolism models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Phosphatases
  • Pathway perturbation studies connected to MAPK / ERK Signaling
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, SPI-112 is appropriate when a defined chemical perturbant is needed to connect Phosphatases with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cell signaling and metabolism models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Phosphatases
Target Class:
Enzyme
Pathways:
MAPK / ERK Signaling
Research Area:
Cell Signaling • Metabolism
CAS No.:
1051387-90-6
Molecular Weight:
468.46
Formula:
C₂₂H₁₇FN₄O₅S
SMILES:
C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)F)O)C(=O)O
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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