SR-717 lithium
Selleck Chemicals
SKU:S0853-5MG
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SR-717 lithium is an agonist of PD-1 / PD-L1 used in studies of Immune Signaling. In practice, this places the compound in experiments that measure cytokine-mediated signaling and inflammatory effector responses in cancer, immunology, and inflammation models.
By activating PD-1 / PD-L1, SR-717 lithium can be used to examine cytokine-mediated signaling and inflammatory effector responses. The immunomodulator annotation adds relevance to immune-cell activation, cytokine, and mediator assays, together with downstream-response mapping in the same experimental setting. In cancer, immunology, and inflammation models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving PD-1 / PD-L1
- Pathway perturbation studies connected to Immune Signaling
- Agonist-response and downstream signaling studies
- Immune-cell activation, cytokine, and mediator assays
Overall, SR-717 lithium is appropriate when a defined chemical perturbant is needed to connect PD-1 / PD-L1 with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, immunology, and inflammation models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- PD-1 / PD-L1
- Target Class:
- Immunomodulator
- Pathways:
- Immune Signaling
- Research Area:
- Cancer • Immunology • Inflammation
- CAS No.:
- 2375421-09-1
- Molecular Weight:
- 351.19
- Formula:
- C₁₅H₈F₂LiN₅O₃
- SMILES:
- [Li]OC(=O)C1=C(NC(=O)C2=NN=C(C=C2)[N]3C=CN=C3)C=C(F)C(=C1)F
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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