SRC Antibody - FFPE Validated
BiCell Scientific
SKU:53106-FFPE-50UL
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Scientific Overview
Use this antibody to characterize SRC when mapping complex behavior and signaling context. SRC is a signaling protein that can relay information through phosphorylation and complex assembly. Many projects interpret this target alongside interacting partners, upstream cues, and downstream readouts.
Following SRC across perturbations can help separate expression effects from compartment shifts.
Research Relevance
Perturbations such as inhibitors or ligand stimulation can drive rapid shifts in localization or complex formation. Considering complex membership and compartment shifts can clarify whether changes reflect signaling or redistribution.
Since many cellular processes are coupled, measured differences can reflect both direct regulation and indirect effects from broader state changes. Developmental projects may follow this target across stage-dependent remodeling and tissue patterning.
When building a narrative around the target, it helps to track:
- condition-to-condition comparisons with matched controls
- interaction patterns within multi-protein complexes
- time-resolved changes following stimulation or inhibition
Application-Specific Context
Because fixation can mask epitopes, fixed-section oriented formats aim to maintain recognition after standard deparaffinization and retrieval steps. Think about how preparation affects epitope accessibility, and interpret patterns alongside morphology and compartment markers as needed. If signaling is transient, sampling time can be as important as condition.
To support downstream analysis, record key context variables (culture timing, stimulation window, and extraction approach) so SRC patterns can be compared across experiments without guesswork.
Use the fixed-section version to relate SRC behavior to upstream cues and downstream consequences.
- Targets:
- SRC
- Research Area:
- Cell Signaling • Developmental Biology • Stem Cell Biology
- Application:
- IHC-P
- Reactivity:
- Human • Mouse • Rat
- Host:
- Rat
- Clonality:
- Polyclonal
- Isotype:
- IgG
- Immunogen:
- Synthetic peptide (16-aa) derived from the N-terminal region of human SRC protein
- Conjugation:
- Unconjugated
- Purification:
- Affinity Chromatography
- Concentration:
- 0.25 mg/ml
- UniProt:
- P12931
- Homology:
- Synthetic peptide sequence is identical to mouse or rat sequence
- Storage Buffer:
- PBS, pH 7.2, 0.1% Sodium Azide
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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The purchase of this product does not grant any license for commercial use, manufacturing, or clinical applications. The user is responsible for ensuring compliance with applicable laws and third-party rights.