SRI-011381 hydrochloride
Selleck Chemicals
SKU:E4798-5MG
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SRI-011381 hydrochloride is an agonist of TGF-beta / Smad used in studies of TGF-beta / Smad Signaling. In practice, this places the compound in experiments that measure Smad-mediated transcription, differentiation, and fibrotic signaling in cancer, cell signaling, and developmental biology models.
By activating TGF-beta / Smad, SRI-011381 hydrochloride can be used to examine Smad-mediated transcription, differentiation, and fibrotic signaling. The signaling pathway modulator annotation adds relevance to pathway-reporter and mechanistic-phenotyping studies, together with downstream-response mapping in the same experimental setting. In cancer, cell signaling, and developmental biology models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.
Research Applications
- Target-focused assays involving TGF-beta / Smad
- Pathway perturbation studies connected to TGF-beta / Smad Signaling
- Agonist-response and downstream signaling studies
- Pathway-reporter and mechanistic-phenotyping studies
Overall, SRI-011381 hydrochloride is appropriate when a defined chemical perturbant is needed to connect TGF-beta / Smad with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in cancer, cell signaling, and developmental biology models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.
- Targets:
- TGF-beta / Smad
- Target Class:
- Signaling Pathway Modulator
- Pathways:
- TGF-beta / Smad Signaling
- Research Area:
- Cancer • Cell Signaling • Developmental Biology
- CAS No.:
- 2070014-88-7
- Molecular Weight:
- 365.94
- Formula:
- C₂₀H₃₁N₃O·ClH
- Storage Temperature:
- -20°C
For Research Use Only. Not intended for diagnostic or therapeutic use.
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