Suramin sodium salt

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Selleck Chemicals

S8942-5MG

€186,00 EUR
€186,00 EUR
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Suramin sodium salt is an inhibitor of Phosphatases and Sirtuins and related targets used in studies of DNA Damage Response and Epigenetic Regulation and related signaling programs. It is especially relevant in aging, cancer, and cell signaling models, where defined compound exposure can be linked to checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation.

By inhibiting Phosphatases and Sirtuins and related targets, Suramin sodium salt can be used to examine checkpoint activation, DNA repair, and genome-stability control and chromatin-state control, histone modification, and transcriptional regulation. The enzyme annotation adds relevance to enzyme-activity assays, substrate-conversion studies, and mechanism profiling, together with downstream-response mapping in the same experimental setting. In aging, cancer, and cell signaling models, these readouts can be combined with viability, reporter, localization, biochemical conversion, or morphology endpoints to refine experimental interpretation.

Research Applications

  • Target-focused assays involving Phosphatases and Sirtuins and related targets
  • Pathway perturbation studies connected to DNA Damage Response and Epigenetic Regulation and related signaling programs
  • Concentration-response inhibition and target-dependence studies
  • Enzyme-activity assays, substrate-conversion studies, and mechanism profiling

Overall, Suramin sodium salt is appropriate when a defined chemical perturbant is needed to connect Phosphatases and Sirtuins and related targets with measurable biochemical, transcriptional, electrophysiological, imaging, or phenotypic readouts in aging, cancer, and cell signaling models. This profile is suited to mechanistic follow-up, comparative profiling, and assay optimization under defined exposure conditions.

Targets:
Phosphatases • Sirtuins • Topoisomerase
Target Class:
Enzyme
Pathways:
DNA Damage Response • Epigenetic Regulation • Viral Entry / Replication
Research Area:
Aging • Cancer • Cell Signaling • DNA Damage / Repair
CAS No.:
129-46-4
Molecular Weight:
1435.23
Formula:
C₅₁H₄₀N₆O₂₃S₆·6Na
SMILES:
CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)[O-])S(=O)(=O)[O-])S(=O)(=O)[O-])C.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Storage Temperature:
-20°C

For Research Use Only. Not intended for diagnostic or therapeutic use.
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